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Internal Medicine & Pediatrics of San Diego

Thoughtful care for every chapter of life

Thoughtful, long-term primary care for newborns, children, adults, and seniors delivered by a team that knows your family.
  • 65+ years combined experience
  • Whole-family care
  • Same day appointments available
Contact Us

Internal Medicine & Pediatrics of San Diego

Thoughtful care for every chapter of life

Thoughtful, long-term primary care for newborns, children, adults, and seniors delivered by a team that knows your family.
  • 65+ years combined experience
  • Whole-family care
Contact Us

Internal Medicine & Pediatrics of San Diego brings adult healthcare and pediatric care together in one welcoming practice.

From preventive medicine to ongoing condition management, we provide continuity patients can rely on for years.

One practice, every generation

Healthcare built around
lasting relationships.

One practice, every generation

Healthcare built around
lasting relationships.

Internal Medicine & Pediatrics of San Diego brings adult healthcare and pediatric care together in one welcoming practice.

From preventive medicine to ongoing condition management, we provide continuity patients can rely on for years.

HOW WE CAN HELP

Care for every stage of life.

Our Providers

Our providers have combined 65+ years of experience treating adults and children.

Meet Our Providers →

Insurance

We accept most major health insurance plans and help patients understand their coverage.

Learn More →

Services

We provide comprehensive medical care from childhood through adulthood.

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Our Providers

Our providers have a combined 65+ years of experience treating adults and children.

Meet Our Providers
Insurance

We are affiliated with Sharp Community Medical Group. We accept most health insurance plans.

Learn More
Services

We provide a whole myriad of medical care from birth to adulthood to senior care.

Explore Services

Our practice

Experience that spans generations.

Our providers have a combined 65+ years of experience treating adults and children with careful listening and coordinated care.
Meet Our Providers

Trusted by

Trusted by families across San Diego.

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Verified Patient

“Dr. Mansour is the BEST!”

Verified Patient

“I’ve been going to Jennifer Lyons for years and she is one of my coworkers’ favorites. She listens, and is very professional yet personable.”

Verified Patient

Dr. Mansour has been my doctor for over 10 years. He always takes the time to listen, he asks questions about all aspects of my health and I leave the visit feeling completely cared for. I'm so glad Dr. Mansour is my doctor and I would and have recommended him to colleagues.

Trusted by

Trusted by families across San Diego.

Call Now
Verified Patient

“Dr. Mansour is the BEST!”

Verified Patient

“I’ve been going to Jennifer Lyons for years and she is one of my coworkers’ favorites. She listens, and is very professional yet personable.”

Verified Patient

Dr. Mansour has been my doctor for over 10 years. He always takes the time to listen, he asks questions about all aspects of my health and I leave the visit feeling completely cared for. I'm so glad Dr. Mansour is my doctor and I would and have recommended him to colleagues.

Questions or appointments

We are happy to help

Our San Diego care team is ready to help.
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Compassionate care, close to home

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Our San Diego care team is ready to help.

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Amianne Huffman

Amianne Huffman, PA-C, is a San Diego native with 10 years of experience as a Physician Assistant, all in primary care. She earned her Bachelor of Science in Biochemistry from the University of California, San Diego, and her Master of Physician Assistant Studies from the University of North Texas Health Science Center.

Her passion for caring for others began before PA school, when she worked as an EMT and gained experience in the emergency room. She always knew she wanted a career in medicine that would allow her to work directly with patients, and after completing her training, primary care was exactly where she wanted to be.

She enjoys the variety that primary care offers, with special interests in women’s health, perimenopause and menopause, geriatrics, weight management, and mental health. She is passionate about preventive care and early disease detection, as well as helping patients effectively manage chronic health conditions.

She believes the best healthcare is a partnership. Her goal is to work alongside each patient to understand their individual needs and health goals while providing thoughtful recommendations based on the best available medical evidence. She values creating a comfortable environment where patients feel heard, informed, and actively involved in decisions about their care.

Her dedication to her patients has been recognized with the Top Advanced Practice Clinician Award for Patient Satisfaction in both 2024 and 2025.

Born and raised in San Diego, she is proud to care for patients in the community she has always called home. Outside of medicine, she enjoys spending time with her husband and their two children.

Jennifer Lyons, MS, PA-C

Jennifer Lyons, PA-C, brings 25 years of experience in primary care to Internal Medicine & Pediatrics of San Diego. Originally from the suburbs of Chicago, Jen earned Bachelor of Science degrees in Nursing and Psychology from Elmhurst College before completing her Master of Science in Physician Assistant Studies in 2001. She relocated to San Diego in 2008 and has spent much of her career caring for patients in the San Diego community.

One of the things Jen values most about primary care is the opportunity to build lasting relationships with her patients and their families. She enjoys getting to know her patients over the years, understanding what is important to them, and being a trusted partner through the many different stages of their lives.

Jen enjoys the broad scope of primary care and has particular interests in preventive medicine, migraines, weight management, mental health, women’s health and menopause, and helping patients manage both acute and chronic health concerns. Her approach is individualized, recognizing that being healthy means something different for every patient.

At the center of Jen’s philosophy is a simple goal: to work together with her patients to help them live their happiest and healthiest lives. She believes patients should feel heard, comfortable asking questions, and actively involved in decisions about their health.

Jen’s commitment to her patients has been recognized with the Top Advanced Practice Clinician Award for Patient Satisfaction in both 2024 and 2025.

Outside of medicine, Jen enjoys spending time with her two children and embracing the Southern California community she has called home since 2008.

Karim Mansour, MD

Dr. Mansour has been in practice for over 30 years, almost all of it through affiliation with Sharp Community Medical Group. He attended Albany Medical College in New York. Internship and Residency were completed at Loma Linda University in Southern California and has been in San Diego since 1996.  He is dual board-certified in Internal Medicine and in Pediatrics. He sees newborns to geriatric patients. He has admitting privileges at Sharp Memorial Hospital, where he provided hospitalist care to adult patients for 30 years, gaining valuable experience in treating inpatients with serious medical conditions.  He has also had attending privileges at Sharp March Birch Hospital, where he cared for newborns. Dr. Mansour also attended to pediatric patients at Sharp Mesa Vista Hospital. 

Over the years, Dr. Mansour has been voted Top Doctor in San Diego by his peers multiple times.  

Dr. Mansour has an interest in cultivating rare fruit trees.  He has a large collection of various hard-to-find fruit trees that thrive in our beautiful San Diego climate.